International Biological and Medical Journals Publishing House Co., Limited
 
ISSN  2411-2917
Key title:
Infectious Diseases and Translational Medicine
Abbreviated key title:
Infect. Dis. Transl. Med.
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Ruifu Yang, Beijing
Publisher Name: International Biological and Medical Journals Publishing House Co., Limited
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Factors Contributing to High Frequency of Epidemic Manifestations of Plague on Madagascar
Peculiarities of plague epizootiology and epidemiology on Madagascar over the period of 1898-2017 and outbreaks of pneumonic plague, 2017 are analyzed in this paper. Summarized have been the literature data and our own e ...More>>
DOI: 10.11979/idtm.201801004
Genomic Evidence for Discrimination and Transmission of a Hyperepidemic Vibrio cholerae Clone
Molecular subtyping of the bacterial pathogens provides an unconventional strategy from the traditional epidemic methods in the infectious disease surveillance, outbreak detection and source tracing. Particularly, microb ...More>>
DOI: 10.11979/idtm.201801001
 
Current Issue Accepted Online First Archive Most Downloaded
  2018, 4(1)   Published: 30 November 2018
 
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       News and Views
Genomic Evidence for Discrimination and Transmission of a Hyperepidemic Vibrio cholerae Clone Hot!
Bo Pang, Biao Kan
2018, 4(1): 1-3 | [ PDF (784 KB) ] ( 91 )
DOI:10.11979/idtm.201801001
Abstract
Molecular subtyping of the bacterial pathogens provides an unconventional strategy from the traditional epidemic methods in the infectious disease surveillance, outbreak detection and source tracing. Particularly, microbial genome sequencing unfolds the variance of the bacterial pathogens in the nucleotide level, it has been used rapidly and widely in the epidemiological investigations. By using the genome sequencing, we compared the genomes of the strains from cholera outbreak in China in 1995, with those from Haiti outbreak started in 2010 and other global isolates. Though the Chinese and Haiti outbreak strains have the quite similar pulsed-field gel electrophoresis (PFGE) patterns, the genome-based phylogeny showed their close but clearly different positions in the branches, and all are closely related to the early epidemic strains from South Asia. Strain genome comparison provided much more abundant and accurate evidence than PFGE. Therefore, combined with epidemiological data, genome sequencing may reveal much more effectively the evolutionary relationship, identify the hyperepidemic clone and re-construct the transmission routes among the different regions. This case may also show that technical transition from PFGE to microbial genome sequencing in the infectious disease surveillance laboratory network is imperative to be promoted.
Attenuating Type Ⅰ Interferon Responses During Viral Entry: a New Legend for Viral Survival
Jian Chen, Xiaoyan Zhang, Jia Liu, Jianqing Xu
2018, 4(1): 4-5 | [ PDF (608 KB) ] ( 75 )
DOI:10.11979/idtm.201801002
Abstract
Archaeome: an Underrated Player in Human Microbiome
Xiang Li, Yujing Bi
2018, 4(1): 6-6 | [ PDF (606 KB) ] ( 66 )
DOI:10.11979/idtm.201801003
Abstract
       Review
Factors Contributing to High Frequency of Epidemic Manifestations of Plague on Madagascar Hot!
A.Yu. Popova, S.A. Shcherbakova, Ya.V. Sizova, N.V. Popov, G.A. Eroshenko, S.A. Bugorkova, V.P. Toporkov, V.V. Kutyrev
2018, 4(1): 7-13 | [ PDF (986 KB) ] ( 143 )
DOI:10.11979/idtm.201801004
Abstract
Peculiarities of plague epizootiology and epidemiology on Madagascar over the period of 1898-2017 and outbreaks of pneumonic plague, 2017 are analyzed in this paper. Summarized have been the literature data and our own experimental data, characterizing the properties of Yersinia pestis strains isolated on Madagascar in the twentieth century. Existence of natural, natural-anthropourgic, and anthropourgic plague foci on Madagascar has been substantiated. Epidemiological consequences of Y. pestis transmission over the borders of natural foci and import of plague agent into residential areas are discussed. Assessed has also been the system of preventive (anti-epidemic) measures, aimed at stabilization of plague incidence in the territory of Madagascar Island.
 
 
 
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